Brugada Syndrome

First described in 1992, Brugada Syndrome is comprised of a predisposition to ventricular tachyarrhythmias, sometimes leading to sudden cardiac death, especially while at rest or in association with a fever, in the presence of right bundle branch block and precordial lead ST elevation.

Brugada Syndrome (BS) is more common in men under forty years of age and is thought to be a leading cause of sudden cardiac arrest in this age population. The patient may or may not have a family history of sudden cardiac arrest. The patient may or may not have symptoms of syncope or cardiac arrest. What will be present, however, is ST elevation in the precordial leads. 

Previously, electrophysiologic studies were recommended to determine the inducibility of arrhythmias. Such studies are no longer recommended, although some clinicians still perform them. The treatment of choice is placement of an ICD (implantable cardiac defibrillator). ICD placement is only recommended in these patients who have had a cardiac arrest or have a family history of early cardiac arrest, otherwise, ICD is not recommended.